| 1 | SerA | 01/06/2022 | Juventus - Napoli | 1 - 1 | Szczęsny | Mertens | 23' fp | 0 - 1 |
| 2 | CI | 01/18/2022 | Juventus - Sampdoria | 4 - 1 | Perin | Conti A. | 18' sp | 2 - 1 |
| 3 | CI | 02/10/2022 | Juventus - Sassuolo | 2 - 1 | Perin | Traorè | 24' fp | 1 - 1 |
| 4 | SerA | 02/18/2022 | Juventus - Torino | 1 - 1 | Szczęsny | Belotti | 17' sp | 1 - 1 |
| 5 | UCL | 03/16/2022 | Juventus - Villarreal (SPA) | 0 - 3 | Szczęsny | Moreno penalty | 33' sp | 0 - 1 |
| 6 | UCL | 03/16/2022 | Juventus - Villarreal (SPA) | 0 - 3 | Szczęsny | Torres | 40' sp | 0 - 2 |
| 7 | UCL | 03/16/2022 | Juventus - Villarreal (SPA) | 0 - 3 | Szczęsny | Danjuma penalty | 47' sp | 0 - 3 |
| 8 | SerA | 04/03/2022 | Juventus - Inter | 0 - 1 | Szczęsny | Çalhanoğlu penalty | 50' fp | 0 - 1 |
| 9 | SerA | 04/16/2022 | Juventus - Bologna | 1 - 1 | Szczęsny | Arnautović | 7' sp | 0 - 1 |
| 10 | SerA | 05/01/2022 | Juventus - Venezia | 2 - 1 | Szczęsny | Aramu | 26' sp | 1 - 1 |
| 11 | SerA | 05/16/2022 | Juventus - Lazio | 2 - 2 | Perin | Alex Sandro own goal | 6' sp | 2 - 1 |
| 12 | SerA | 05/16/2022 | Juventus - Lazio | 2 - 2 | Perin | Milinković-Savić S. | 51' sp | 2 - 2 |
| 13 | SerA | 08/27/2022 | Juventus - Roma | 1 - 1 | Szczęsny | Abraham | 24' sp | 1 - 1 |
| 14 | SerA | 09/11/2022 | Juventus - Salernitana | 2 - 2 | Perin | Candreva | 18' fp | 0 - 1 |
| 15 | SerA | 09/11/2022 | Juventus - Salernitana | 2 - 2 | Perin | Piątek penalty | 50' fp | 0 - 2 |
| 16 | UCL | 09/14/2022 | Juventus - Benfica Lisbona (POR) | 1 - 2 | Perin | João Mário penalty | 43' fp | 1 - 1 |
| 17 | UCL | 09/14/2022 | Juventus - Benfica Lisbona (POR) | 1 - 2 | Perin | Neres | 10' sp | 1 - 2 |
| 18 | UCL | 10/05/2022 | Juventus - Maccabi Haifa (ISR) | 3 - 1 | Szczęsny | David | 30' sp | 2 - 1 |
| 19 | UCL | 11/02/2022 | Juventus - Paris Saint-Germain (FRA) | 1 - 2 | Szczęsny | Mbappé | 13' fp | 0 - 1 |
| 20 | UCL | 11/02/2022 | Juventus - Paris Saint-Germain (FRA) | 1 - 2 | Szczęsny | Mendes | 24' sp | 1 - 2 |
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