| 1 | SerA | 06/01/2022 | Juventus - Napoli | 1 - 1 | Szczęsny | Mertens | 23' pt | 0 - 1 |
| 2 | CI | 18/01/2022 | Juventus - Sampdoria | 4 - 1 | Perin | Conti A. | 18' st | 2 - 1 |
| 3 | CI | 10/02/2022 | Juventus - Sassuolo | 2 - 1 | Perin | Traorè | 24' pt | 1 - 1 |
| 4 | SerA | 18/02/2022 | Juventus - Torino | 1 - 1 | Szczęsny | Belotti | 17' st | 1 - 1 |
| 5 | UCL | 16/03/2022 | Juventus - Villarreal (SPA) | 0 - 3 | Szczęsny | Moreno rigore | 33' st | 0 - 1 |
| 6 | UCL | 16/03/2022 | Juventus - Villarreal (SPA) | 0 - 3 | Szczęsny | Torres | 40' st | 0 - 2 |
| 7 | UCL | 16/03/2022 | Juventus - Villarreal (SPA) | 0 - 3 | Szczęsny | Danjuma rigore | 47' st | 0 - 3 |
| 8 | SerA | 03/04/2022 | Juventus - Inter | 0 - 1 | Szczęsny | Çalhanoğlu rigore | 50' pt | 0 - 1 |
| 9 | SerA | 16/04/2022 | Juventus - Bologna | 1 - 1 | Szczęsny | Arnautović | 7' st | 0 - 1 |
| 10 | SerA | 01/05/2022 | Juventus - Venezia | 2 - 1 | Szczęsny | Aramu | 26' st | 1 - 1 |
| 11 | SerA | 16/05/2022 | Juventus - Lazio | 2 - 2 | Perin | Alex Sandro autorete | 6' st | 2 - 1 |
| 12 | SerA | 16/05/2022 | Juventus - Lazio | 2 - 2 | Perin | Milinković-Savić S. | 51' st | 2 - 2 |
| 13 | SerA | 27/08/2022 | Juventus - Roma | 1 - 1 | Szczęsny | Abraham | 24' st | 1 - 1 |
| 14 | SerA | 11/09/2022 | Juventus - Salernitana | 2 - 2 | Perin | Candreva | 18' pt | 0 - 1 |
| 15 | SerA | 11/09/2022 | Juventus - Salernitana | 2 - 2 | Perin | Piątek rigore | 50' pt | 0 - 2 |
| 16 | UCL | 14/09/2022 | Juventus - Benfica Lisbona (POR) | 1 - 2 | Perin | João Mário rigore | 43' pt | 1 - 1 |
| 17 | UCL | 14/09/2022 | Juventus - Benfica Lisbona (POR) | 1 - 2 | Perin | Neres | 10' st | 1 - 2 |
| 18 | UCL | 05/10/2022 | Juventus - Maccabi Haifa (ISR) | 3 - 1 | Szczęsny | David | 30' st | 2 - 1 |
| 19 | UCL | 02/11/2022 | Juventus - Paris Saint-Germain (FRA) | 1 - 2 | Szczęsny | Mbappé | 13' pt | 0 - 1 |
| 20 | UCL | 02/11/2022 | Juventus - Paris Saint-Germain (FRA) | 1 - 2 | Szczęsny | Mendes | 24' st | 1 - 2 |
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