| 1 | SerA | 08/22/2021 | Udinese - Juventus | 2 - 2 | Szczęsny | Pereyra penalty | 6' sp | 1 - 2 |
| 2 | SerA | 08/22/2021 | Udinese - Juventus | 2 - 2 | Szczęsny | Deulofeu | 38' sp | 2 - 2 |
| 3 | SerA | 08/28/2021 | Juventus - Empoli | 0 - 1 | Szczęsny | Mancuso | 21' fp | 0 - 1 |
| 4 | SerA | 09/11/2021 | Napoli - Juventus | 2 - 1 | Szczęsny | Politano | 12' sp | 1 - 1 |
| 5 | SerA | 09/11/2021 | Napoli - Juventus | 2 - 1 | Szczęsny | Koulibaly | 40' sp | 2 - 1 |
| 6 | SerA | 09/19/2021 | Juventus - Milan | 1 - 1 | Szczęsny | Rebić | 31' sp | 1 - 1 |
| 7 | SerA | 09/22/2021 | Spezia - Juventus | 2 - 3 | Szczęsny | Gyasi | 33' fp | 1 - 1 |
| 8 | SerA | 09/22/2021 | Spezia - Juventus | 2 - 3 | Szczęsny | Antiste | 4' sp | 2 - 1 |
| 9 | SerA | 09/26/2021 | Juventus - Sampdoria | 3 - 2 | Perin | Yoshida | 44' fp | 2 - 1 |
| 10 | SerA | 09/26/2021 | Juventus - Sampdoria | 3 - 2 | Perin | Candreva | 38' sp | 3 - 2 |
| 11 | SerA | 10/24/2021 | Inter - Juventus | 1 - 1 | Szczęsny | Džeko | 17' fp | 1 - 0 |
| 12 | SerA | 10/27/2021 | Juventus - Sassuolo | 1 - 2 | Perin | Frattesi | 44' fp | 0 - 1 |
| 13 | SerA | 10/27/2021 | Juventus - Sassuolo | 1 - 2 | Perin | Lopez | 50' sp | 1 - 2 |
| 14 | SerA | 10/30/2021 | Hellas Verona - Juventus | 2 - 1 | Szczęsny | Simeone | 11' fp | 1 - 0 |
| 15 | SerA | 10/30/2021 | Hellas Verona - Juventus | 2 - 1 | Szczęsny | Simeone | 14' fp | 2 - 0 |
| 16 | UCL | 11/02/2021 | Juventus - Zenit FC (RUS) | 4 - 2 | Szczęsny | Bonucci own goal | 26' fp | 1 - 1 |
| 17 | UCL | 11/02/2021 | Juventus - Zenit FC (RUS) | 4 - 2 | Szczęsny | Azmoun | 47' sp | 4 - 2 |
| 18 | UCL | 11/23/2021 | Chelsea (ING) - Juventus | 4 - 0 | Szczęsny | Chalobah | 25' fp | 1 - 0 |
| 19 | UCL | 11/23/2021 | Chelsea (ING) - Juventus | 4 - 0 | Szczęsny | James | 11' sp | 2 - 0 |
| 20 | UCL | 11/23/2021 | Chelsea (ING) - Juventus | 4 - 0 | Szczęsny | Hudson-Odoi | 13' sp | 3 - 0 |
| 21 | UCL | 11/23/2021 | Chelsea (ING) - Juventus | 4 - 0 | Szczęsny | Werner | 50' sp | 4 - 0 |
| 22 | SerA | 11/27/2021 | Juventus - Atalanta | 0 - 1 | Szczęsny | Zapata D. | 28' fp | 0 - 1 |
| 23 | SerA | 12/11/2021 | Venezia - Juventus | 1 - 1 | Szczęsny | Aramu | 10' sp | 1 - 1 |
| 24 | SerA | 01/06/2022 | Juventus - Napoli | 1 - 1 | Szczęsny | Mertens | 23' fp | 0 - 1 |
| 25 | SerA | 01/09/2022 | Roma - Juventus | 3 - 4 | Szczęsny | Abraham | 11' fp | 1 - 0 |
|
|
